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LORIC - The Longitudinal Orthokeratology Research in Children (in Hong Kong: A Pilot Study on Refractive Changes and Myopic Control

iGO SUMMARY:This Hong Kong study comprised a two year assessment of 35 short-sighted children aged between 7 and 12 who underwent Overnight Vision Correction (OVC) using overnight ortho-k corrective contact lenses and compared the results with those for a similar group of children wearing spectacles. The average pre-treatment level of short-sightedness was in excess of two diopters whilst the post-treatment level had reduced on average to less than one-fifth of a diopter. The results demonstrated that OVC is an effective way of correcting short-sightedness in children and the achieved results were stable thus demonstrating that short-sight did not deteriorate any further after commencing OVC.

ABSTRACT

BACKGROUND: This prospective case series was conducted to describe the safety and efficacy of orthokeratology with the EmeraldTM Contact Lens for Overnight Orthokeratology (Oprifocon A; Euclid Systems Corporation, Herndon, Virginia) among young myopes.

METHODS: Twenty subjects (ages 10 to 16) were enrolled in the 6-month pilot study. Subjects were fit empirically with overnight orthokeratology lenses and evaluated at 1 day, 1 week, 1 month, 2 months, 3 months, and 6 months.

RESULTS: Sixteen subjects completed the study. The mean baseline spherical equivalent refraction (SER) was -2.06 diopters (D) (±0.75). The mean SER at 6 months was -0.16 D (±0.38). The mean baseline uncorrected acuity was 0.78 (±0.28) logarithmic minimum angle of resolution (logMAR) equivalent (20/100 Snellen). The mean logMAR equivalent at 6 months was -0.03 ± 0.12 (<20/20 Snellen). On average, 40% of eyes showed some type of corneal staining between the 1-week and 6-month visits. No serious adverse events occurred during the study.

CONCLUSIONS: In contrast to previously published studies that reported maximum results at 2 weeks, subjects reached maximum reduction in myopia at the 1-week visit and, on average, obtained a 92.2% reduction in spherical equivalent refractive error at 6 months. This pilot study lends to a growing body of evidence that short-term correction of mild to moderate myopia with overnight orthokeratology is safe and efficacious in children and adolescents.

May 2007 Optometry, Pauline Cho, Sin Wan Cheung, and Marion Edwards, Department of Optometry & Radiography, The Hong Kong Polytechnic University, Hong Kong, SAR, China  

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